Platelets are formed and released into the bloodstream by precursor cells called megakaryocytes that reside within the bone marrow.
Platelets express and release substances that promote tissue repair and influence processes such as angiogenesis, inflammation and the immune response.
Once platelets are made and circulated into your bloodstream, they live for 8 to 10 days. A normal platelet count is 150,000 to 450,000 platelets per microliter of blood.
During the past several years, much has been written about platelet-rich plasma (PRP) and its potential effectiveness
However the lack of standardisation and inaccurate information regarding platelet concentration, research studies have not definitively proved that PRP works for the conditions it is reported to benefit, and there's a simple and scientific reason for this. To learn more, go to our data page.
Platelets are attracted to platelets and once activated, they will attract more platelets to the site to promote tissue regeneration.
Platelets are tiny fragments of membrane-enclosed cytoplasm. Blood platelets are smaller than both RBC and WBC smallest which is an important consideration during centrifugation.
The α-granules of the platelets are rich in growth factors such as the vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF) and transforming growth factor β (TGF-β), which play a key role in tissue healing:
The majority of growth factors released by platelets target the Fibroblast, which is a biological cell that synthesizes the extracellular matrix and collagen, produces the structural framework.
The α-granules of the platelets are rich in growth factors such as the vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF) and transforming growth factor β (TGF-β), which play a key role in tissue healing.
The biological cascade promotes regeneration of skin and hair, however treatment for osteoarthritis is a specialist field and should only be carried out by specialist doctors due to the high risk of infection.